Description

GHB or Gamma Hydroxybutyrate (C4H8O3) is a central nervous system (CNS) depressant that is commonly referred to as a “club drug” or “date rape” drug. GHB is abused by teens and young adults at bars, parties, clubs and “raves” (all night dance parties), and is often placed in alcoholic beverages.

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Euphoria, increased sex drive, and tranquility are reported positive effects of GHB abuse. Negative effects may include sweating, loss of consciousness, nausea, hallucinations, amnesia, and coma, among other side effects.

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Xyrem (sodium oxybate), a brand name prescription drug was approved by the Food and Drug Administration (FDA) in 2002 for the treatment of narcolepsy, a sleep disorder that causes excessive sleepiness and recurring daytime sleep attacks. It is the sodium salt of gamma hydroxybutyrate. Xyrem is a highly regulated drug in the U.S. GHB is a Schedule III controlled substance, and requires patient enrollment in a restricted access program.

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GHB is also a naturally-occurring metabolite of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) found in the brain. The naturally-occurring metabolite GHB is present in much lower concentrations in the brain than those levels found when the drug is abused. As a result of fermentation, natural Gamma Hydroxybutyrate may also be found in small but insignificant quantities in some beers and wines.

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Gamma Hydroxybutyrate is available as an odorless, colorless drug that may be combined with alcohol and given to unsuspecting victims prior to sexual assaults. It may have a soapy or salty taste. Use for sexual assault has resulted in GHB being known as a “date rape” drug.2 Victims become incapacitated due to the sedative effects of GHB,3 and they are unable to resist sexual assault. It may also induce amnesia in its victim. Common user groups include high school and college students and rave party attendees who use GHB for its intoxicating effects.

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Emergency department episodes related to the use of club drugs (GHB) usually involve the use of multiple substances, such as marijuana, cocaine,4 and other club drugs, such as methamphetamine, Ecstasy, or Rohypnol.

Other names; Liquid Ecstasy, Gamma Hydroxybutyrate, Liquid X, Liquid E, Georgia Home Boy, Soap, Scoop, Cherry Meth, Blue Nitro, Fishies, G, Fantasy, Grievous Bodily Harm